Proteomics in Medicine

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چکیده

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Proteomics in Medicine

Proteomics is the identification of proteins in a tissue or cell, and the determination of their function, structure and modifications [1,2]. The term proteome was coined by Marc Wilkins to describe all the proteins expressed by a genome [1]. It is considered to be the next step in modern biology. Proteomics is dynamic compared to genomics because it changes constantly to reflect the cell’s env...

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The study of the genome dictated that the whole is more than the sum of its parts; genes do not function independently but in networks. The impact of this understanding was explosive. It acknowledged the concept that this interplay of genes is at least equally significant to their individual functions, and indicated that genome alone cannot describe the whole of an organism, not without the stu...

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Application of proteomics in Chinese medicine research.

Proteomics technologies can be applied to simultaneously study the function, organization, diversity, and dynamic variety of a cell or a whole tissue. The integrative approach of proteomics is in line with the holistic concept and practices of traditional Chinese medicine (TCM). In this review, the technologies of proteomics, their adoption leverages the depth and breadth of TCM research are in...

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[Proteomics and its role in medicine].

Proteomics is a new methodological and conceptual approach to the study of live systems, which aims to map the whole proteom - the protein complement of genome. It aspires to describe quantitatively and qualitatively all proteins present at the given moment in the cell, tissue or the organism. The principal tools of proteomics are separation techniques based on electrophoresis and chromatograph...

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The sequencing of the human genome is undoubtedly one of the major accomplishments of biomedical science.1,2 Knowledge of the precise sequence of all human genes provides unparalleled access to a complete understanding of human biology in all of its complexity. Or does it? The completion of the human genome sequence showed far fewer genes than expected, 30 000, which is not that different from ...

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ژورنال

عنوان ژورنال: Journal of Data Mining in Genomics & Proteomics

سال: 2016

ISSN: 2153-0602

DOI: 10.4172/2153-0602.1000e126